Growing new organs to replace the old--not so far away: Human liver cells seeded in mouse expands 50-fold to functional organoid: Scientists work out the cellular assembly for seeding a whole new organ.
Being able to grow your own new organs may be in reach—with some cellular assembly required.
With a carefully constructed clump of cells, mice grew their own functional human liver organoids in a matter of months, researchers report this week in Science Translational Medicine. The cellular organ seeds blossomed in the rodents, expanding 50-fold in that time. They appeared to form complex liver structures, tap into vasculature, and carry out the functions of a normal liver. The critical factor in getting the organoids to take root, the authors report, was having the seed cells arranged just right.